Anisotropic Hydrodynamic Mean-Field Theory for Semiflexible Polymers under Tension

M. Hinczewski and R. R. Netz, Macromolecules, 44, 6972 (2011)

News from Aug 08, 2011

We introduce an anisotropic mean-field approach for the dynamics of semiflexible polymers under intermediate tension, the force range where a chain is partially extended but not in the asymptotic regime of a nearly straight contour. The theory is designed to exactly reproduce the lowest order equilibrium averages of a stretched polymer, and it treats the full complexity of the problem: the resulting dynamics include the coupled effects of long-range hydrodynamic interactions, backbone stiffness, and large-scale polymer contour fluctuations. Validated by Brownian hydrodynamics simulations and comparison to optical tweezer measurements on stretched DNA, the theory is highly accurate in the intermediate tension regime over a broad dynamical range, without the need for additional dynamic fitting parameters. doi
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