Dye conjugated biocompatible magnetite colloids
Within this project magnetite nanoparticles are prepared by thermal decomposition of iron oleate in high boiling organic solvents. These particles are then transferred to aqueous solutions through ligand exchange followed by conjugation to different dyes and polyethylenglycol via EDC/NHS standard techniques and characterized by TEM, SQUID-magnetometry, and UV/VIS-spectroscopy.
Finally, the particles are sent to partner facilities for “in vitro” and “in vivo” testing and further antibody-conjugation.
Grant: EU-FP7, No.: 310337 „CosmoPHOS-nano“
Supervisor: Prof. Dr. M. Giersig
1st contact person: Dr. Michael Hilgendorff