Publications
2024:
Heyne K, Haacke S, Miller RJD. Watching atomically resolved structural dynamics-Blinded by the light. Structure. 2024 Jun 6;32(6):650-651. doi: 10.1016/j.str.2024.05.008. PMID: 38848681.
2023:
- Yang, Yang, Till Stensitzki, Christina Lang, Jon Hughes, Maria Andrea Mroginski, and Karsten Heyne. "Ultrafast Protein Response in the Pfr State of Cph1 Phytochrome." Photochemical & Photobiological Sciences 2023.
Photochem Photobiol Sci 22, 919–930 (2023). https://dx.doi.org/10.1007/s43630-023-00362-z.
2022:
- Zahn, C., T. Stensitzki, and K. Heyne, Femtosecond anisotropy excitation spectroscopy to disentangle the Qx and Qy absorption in chlorophyll a. Chemical Science, 2022. 13(42): p. 12426-12432. https://doi.org/10.1039/D2SC03538C
- Yang, Y.; Stensitzki, T.; Sauthof, L.; Schmidt, A.; Piwowarski, P.; Escobar, F. V.; Michael, N.; Nguyen, A. D.; Szczepek, M.; Brunig, F. N.; Netz, R. R.; Mroginski, M. A.; Adam, S.; Bartl, F.; Schapiro, I.; Hildebrandt, P.; Scheerer, P.; Heyne, K., Ultrafast proton-coupled isomerization in the phototransformation of phytochrome. Nat Chem 2022.
- Heyne, K., Impact of Ultrafast Electric Field Changes on Photoreceptor Protein Dynamics. J Phys Chem B 2022, 126 (3), 581-587.
- Herklotz, F.; Rubin, T.; Sinnreich, M.; Helmke, A.; von Haimberger, T.; Heyne, K., Fast Simultaneous CO2 Gas Temperature and Concentration Measurements by Quantum Cascade Laser Absorption Spectroscopy. Appl Sci-Basel 2022, 12 (10).
- Herklotz, F.; Rubin, T.; von Haimberger, T.; Heyne, K., CO2 Gas Temperature Sensing Near Room Temperature by a Quantum Cascade Laser in Inter Pulse Mode. Photonics 2022, 9/7), 465. https://doi.org/10.3390/photonics9070465
2021:
- Zahn, C.; Stensitzki, T.; Berg, A.; Mahammed, A.; Zacarias, A.; Gross, Z.; Heyne, K., Ultrafast Electron Transfer in a Self-Assembling Sulfonated Aluminum Corrole–Methylviologen Complex. J. Phys. Chem. B 2021, 125, 10571-10577.
- Grandjean, A.; Lustres, J. L. P.; Jung, G., Solvent-Controlled Intermolecular Proton-Transfer Follows an Irreversible Eigen-Weller Model from fs to ns. CHemPhotoChem 2021.
2020:
- Stensitzki, T.; Adam, S.; Schlesinger, R.; Schapiro, I.; Heyne, K., Ultrafast Backbone Protonation in Channelrhodopsin-1 Captured by Polarization Resolved Fs Vis-pump-IR-Probe Spectroscopy and Computational Methods. Molecules 2020, 25 (4).
- Kussicke, A.; Tegtmeier, M.; Buchau, F.; Heyne, K.; Lindinger, A., Spatial and temporal pulse shaping for lateral and depth resolved two-photon excited fluorescence contrast. J Phys B-at Mol Opt 2020, 53 (2).
- Kraskov, A.; Nguyen, A. D.; Goerling, J.; Buhrke, D.; Escobar, F. V.; Lopez, M. F.; Michael, N.; Sauthof, L.; Schmidt, A.; Piwowarski, P.; Yang, Y.; Stensitzki, T.; Adam, S.; Bartl, F.; Schapiro, I.; Heyne, K.; Siebert, F.; Scheerer, P.; Mroginski, M. A.; Hildebrandt, P., Intramolecular Proton Transfer Controls Protein Structural Changes in Phytochrome. Biochemistry-Us 2020, 59 (9), 1023-1037.
2019:
- Kovacs, G. N.; Colletier, J. P.; Grunbein, M. L.; Yang, Y.; Stensitzki, T.; Batyuk, A.; Carbajo, S.; Doak, R. B.; Ehrenberg, D.; Foucar, L.; Gasper, R.; Gorel, A.; Hilpert, M.; Kloos, M.; Koglin, J. E.; Reinstein, J.; Roome, C. M.; Schlesinger, R.; Seaberg, M.; Shoeman, O. L.; Stricker, M.; Boutet, S.; Haacke, S.; Heberle, J.; Heyne, K.; Domratcheva, T.; Barends, T. R. M.; Schlichting, I., Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin. Nat Commun 2019, 10.
- Hupf, E.; Malaspina, L. A.; Holsten, S.; Kleemiss, F.; Edwards, A. J.; Price, J. R.; Kozich, V.; Heyne, K.; Mebs, S.; Grabowsky, S.; Beckmann, J., Proximity Enforced Agostic Interactions Involving Closed-Shell Coinage Metal Ions. Inorg Chem 2019, 58 (24), 16372-16378.
- Heyne, K.; Kuhn, O., Infrared Laser Excitation Controlled Reaction Acceleration in the Electronic Ground State. J Am Chem Soc 2019, 141 (30), 11730-11738.
2018:
- Stensitzki, T.; Yang, Y.; Kozich, V.; Ahmed, A. A.; Kossl, F.; Kuhn, O.; Heyne, K., Acceleration of a ground-state reaction by selective femtosecond-infrared-laser-pulse excitation. Nat Chem 2018, 10 (2), 126-131.
- Rubin, T. M.; Heyne, K.; Luchterhand, A.; Bednarsch, J.; Vondran, F. W. R.; Polychronidis, G.; Malinowski, M.; Nikolic, A.; Tautenhahn, H. M.; Jara, M.; Wunsch, T.; Stockmann, M.; Lock, J. F., Kinetic validation of the LiMAx test during 10000 intravenous C-13-methacetin breath tests. J Breath Res 2018, 12 (1).
- Kussicke, A.; Tegtmeier, M.; Patas, A.; Buchau, F.; Heyne, K.; Lindinger, A., Combined temporal and spatial laser pulse shaping for two-photon excited fluorescence contrast improvement. Appl Phys B-Lasers O 2018, 124 (12).
- Hassan, I.; Donati, L.; Stensitzki, T.; Keller, B. G.; Heyne, K.; Imhof, P., The vibrational spectrum of the hydrated alanine-leucine peptide in the amide region from IR experiments and first principles calculations. Chem Phys Lett 2018, 698, 227-233.
- Buchau, F.; Patas, A.; Yang, Y.; Lindinger, A.; Heyne, K., A stage-scanning two-photon microscope equipped with a temporal and a spatial pulse shaper: Enhance fluorescence signal by phase shaping. Rev Sci Instrum 2018, 89 (12).
2012-2017:
- Zahn, C.; Stensitzki, T.; Gerecke, M.; Berg, A.; Mahammed, A.; Gross, Z.; Heyne, K., Ultrafast Dynamics of Sb-Corroles: A Combined Vis-Pump Supercontinuum Probe and Broadband Fluorescence Up-Conversion Study. Molecules 2017, 22 (7).
- Stensitzki, T.; Yang, Y.; Wolke, A. L.; Knapp, E. W.; Hughes, J.; Mroginski, M. A.; Heyne, K., Influence of Heterogeneity on the Ultrafast Photoisomerization Dynamics of Pfr in Cph1 Phytochrome. Photochem Photobiol 2017, 93 (3), 703-712.
- Yang, Y.; Heyne, K.; Mathies, R. A.; Dasgupta, J., Non-Bonded Interactions Drive the Sub-Picosecond Bilin Photoisomerization in the P-fr State of Phytochrome Cph1. Chemphyschem 2016, 17 (3), 369-374.
- Stensitzki, T.; Yang, Y.; Muders, V.; Schlesinger, R.; Heberle, J.; Heyne, K., Femtosecond infrared spectroscopy of channelrhodopsin-1 chromophore isomerization. Struct Dynam-Us 2016, 3 (4).
- Stensitzki, T.; Yang, Y.; Berg, A.; Mahammed, A.; Gross, Z.; Heyne, K., Ultrafast electronic and vibrational dynamics in brominated aluminum corroles: Energy relaxation and triplet formation. Struct Dynam-Us 2016, 3 (4).
- Rubin, T.; von Haimberger, T.; Helmke, A.; Lock, J.; Stockmann, M.; Heyne, K., Liver Status Assessment by Spectrally and Time Resolved IR Detection of Drug Induced Breath Gas Changes. Photonics-Basel 2016, 3 (2).
- Kossl, F.; Lisaj, M.; Kozich, V.; Heyne, K.; Kuhn, O., Monitoring the alcoholysis of isocyanates with infrared spectroscopy. Chem Phys Lett 2015, 621, 41-45.
- Yang, Y.; Linke, M.; von Haimberger, T.; Matute, R.; Gonzalez, L.; Schmieder, P.; Heyne, K., Active and silent chromophore isoforms for phytochrome Pr photoisomerization: An alternative evolutionary strategy to optimize photoreaction quantum yields. Struct Dynam-Us 2014, 1 (1).
- Linke, M.; Yang, Y.; Zienicke, B.; Hammam, M. A. S.; von Haimberger, T.; Zacarias, A.; Inomata, K.; Lamparter, T.; Heyne, K., Electronic transitions and heterogeneity of the bacteriophytochrome Pr absorption band: An angle balanced polarization resolved femtosecond VIS pump-IR probe study. Biophys J 2013, 105 (8), 1756-1766.
- Yang, Y.; Linke, M.; von Haimberger, T.; Hahn, J.; Matute, R.; Gonzalez, L.; Schmieder, P.; Heyne, K., Real-Time Tracking of Phytochrome's Orientational Changes During Pr Photoisomerization. J Am Chem Soc 2012, 134 (3), 1408-1411.
- Yang, Y.; Jones, D.; von Haimberger, T.; Linke, M.; Wagnert, L.; Berg, A.; Levanon, H.; Zacarias, A.; Mahammed, A.; Gross, Z.; Heyne, K., Assignment of Aluminum Corroles Absorption Bands to Electronic Transitions by Femtosecond Polarization Resolved VIS-Pump IR-Probe Spectroscopy. J Phys Chem A 2012, 116 (3), 1023-1029.
1999-2011:
- Rubin, T.; von Haimberger, T.; Helmke, A.; Heyne, K., Quantitative determination of metabolization dynamics by a real-time (13)CO(2) breath test. J Breath Res 2011, 5 (2).
- Lauer, A.; Dobryakov, A. L.; Kovalenko, S. A.; Fidder, H.; Heyne, K., Dual photochemistry of anthracene-9,10-endoperoxide studied by femtosecond spectroscopy. Phys Chem Chem Phys 2011, 13 (19), 8723-8732.
- Linke, M.; Theisen, M.; von Haimberger, T.; Madjet, M. E. A.; Zacarias, A.; Fidder, H.; Heyne, K., Determining the Three-Dimensional Electronic Transition Dipole Moment Orientation: Influence of an Isomeric Mixture. Chemphyschem 2010, 11 (6), 1283-1288.
- Heyne, K.; Yang, Y.; Linke, M.; Hahn, J.; Schmieder, P., Determination of the Isomerization Dynamics and Transient Ring D Orientation Changes of the Phytochrome Pfr form in Solution by Polarization Resolved Femtosecond VIS Pump - IR Probe Spectroscopy. Biophys J 2010, 98 (3), 743a-744a.
- Theisen, M.; Linke, M.; Kerbs, M.; Fidder, H.; Madjet, M. E. A.; Zacarias, A.; Heyne, K., Femtosecond polarization resolved spectroscopy: A tool for determination of the three-dimensional orientation of electronic transition dipole moments and identification of configurational isomers. J Chem Phys 2009, 131 (12).
- Stockmann, M.; Lock, J. F.; Riecke, B.; Heyne, K.; Martus, P.; Fricke, M.; Lehmann, S.; Niehues, S. M.; Schwabe, M.; Lemke, A. J.; Neuhaus, P., Prediction of Postoperative Outcome After Hepatectomy With a New Bedside Test for Maximal Liver Function Capacity. Ann Surg 2009, 250 (1), 119-125.
- Fidder, H.; Lauer, A.; Freyer, W.; Koeppe, B.; Heyne, K., Photochemistry of Anthracene-9,10-endoperoxide. J Phys Chem A 2009, 113 (22), 6289-6296.
- Stockmann, M.; Lock, J.; Riecke, B.; Heyne, K.; Martus, P.; Fricke, M.; Lehmann, S.; Niehues, S.; Schwabe, M.; Lemke, A. J.; Neuhaus, P., Postoperative outcome after hepatectomy can be predicted using a new bedside test for maximal liver function capacity. J Hepatol 2008, 48, S97-S98.
- Linke, M.; Lauer, A.; von Haimberger, T.; Zacarias, A.; Heyne, K., Three-Dimensional Orientation of the Q(y) Electronic Transition Dipole Moment within the Chlorophyll a Molecule Determined by Femtosecond Polarization Resolved VIS Pump-IR Probe Spectroscopy. J Am Chem Soc 2008, 130 (45), 14904-+.
- Heyne, K.; Krishnan, G. M.; Kuhn, O., Revealing anharmonic couplings and energy relaxation in DNA oligomers by ultrafast infrared Spectroscopy. J Phys Chem B 2008, 112 (26), 7909-7915.
- Corral, I.; Gonzalez, L.; Lauer, A.; Freyer, W.; Fidder, H.; Heyne, K., Identifying the low-lying electronic states of anthracene-9,10-endoperoxide. Chem Phys Lett 2008, 452 (1-3), 67-71.
- Elsaesser, T.; Huse, N.; Dreyer, J.; Dwyer, J. R.; Heyne, K.; Nibbering, E. T. J., Ultrafast vibrational dynamics and anharmonic couplings of hydrogen-bonded dimers in solution. Chem Phys 2007, 341 (1-3), 175-188.
- Usman, A.; Mohammed, O. F.; Heyne, K.; Dreyer, J.; Nibbering, E. T. J., Excited state dynamics of a PYP chromophore model system explored with ultrafast infrared spectroscopy. Chem Phys Lett 2005, 401 (1-3), 157-163.
- Heyne, K.; Mohammed, O. F.; Usman, A.; Dreyer, J.; Nibbering, E. T. J.; Cusanovich, M. A., Structural evolution of the chromophore in the primary stages of trans/cis isomerization in photoactive yellow protein. J Am Chem Soc 2005, 127 (51), 18100-18106.
- Zemojtel, T.; Rini, M.; Heyne, K.; Dandekar, T.; Nibbering, E. T. J.; Kozlowski, P. M., NO-bound myoglobin: Structural diversity and dynamics of the NO ligand. J Am Chem Soc 2004, 126 (7), 1930-1931.
- Heyne, K.; Nibbering, E. T. J.; Elsaesser, T.; Petkovic, M.; Kuhn, O., Cascaded energy redistribution upon O-H stretching excitation in an intramolecular hydrogen bond. J Phys Chem A 2004, 108 (29), 6083-6086.
- Heyne, K.; Huse, N.; Dreyer, J.; Nibbering, E. T. J.; Elsaesser, T.; Mukamel, S., Coherent low-frequency motions of hydrogen bonded acetic acid dimers in the liquid phase. J Chem Phys 2004, 121 (2), 902-913.
- Huse, N.; Heyne, K.; Dreyer, J.; Nibbering, E. T. J.; Elsaesser, T., Vibrational multilevel quantum coherence due to anharmonic couplings in intermolecular hydrogen bonds. Phys Rev Lett 2003, 91 (19).
- Heyne, K.; Huse, N.; Nibbering, E. T. J.; Elsaesser, T., Coherent vibrational dynamics of intermolecular hydrogen bonds in acetic acid dimers studied by ultrafast mid-infrared spectroscopy. J Phys-Condens Mat 2003, 15 (1), S129-S136.
- Heyne, K.; Huse, N.; Nibbering, E. T. J.; Elsaesser, T., Ultrafast coherent nuclear motions of hydrogen bonded carboxylic acid dimers. Chem Phys Lett 2003, 369 (5-6), 591-596.
- Heyne, K.; Huse, N.; Nibbering, E. T. J.; Elsaesser, T., Ultrafast relaxation and anharmonic coupling of O-H stretching and bending excitations in cyclic acetic acid dimers. Chem Phys Lett 2003, 382 (1-2), 19-25.
- Heyne, K.; Herbst, J.; Stehlik, D.; Esteban, B.; Lamparter, T.; Hughes, J.; Diller, R., Ultrafast dynamics of phytochrome from the cyanobacterium Synechocystis, reconstituted with phycocyanobilin and phycoerythrobilin. Biophys J 2002, 82 (2), 1004-1016.
- Herbst, J.; Heyne, K.; Diller, R., Femtosecond infrared spectroscopy of bacteriorhodopsin chromophore isomerization. Science 2002, 297 (5582), 822-825.
- Heyne, K.; Herbst, J.; Dominguez-Herradon, B.; Alexiev, U.; Diller, R., Reaction control in bacteriorhodopsin: Impact of arg82 and asp85 on the fast retinal isomerization, studied in the second site revertant arg82ala/gly231cys and various purple and blue forms of bacteriorhodopsin. J Phys Chem B 2000, 104 (25), 6053-6058.
- Dziewior, R.; Romey, K.; Diller, R., Femtosecond time resolved infrared spectroscopy of the ethylenic stretch vibration during the all-trans to 13-cis isomerization of bacteriorhodopsin. Laser Chem 1999, 19 (1-4), 173-178.