Hello, my name is Pit Langner. After finishing my Master’s Thesis I rejoined the AG Heberle in 2017 for my PhD. Currently, I am in charge of maintaining and augmenting the infrared spectrometer setup developed by Bernd-Joachim Schulz, which is based on tunable quantum cascade lasers as probing light source and provides the means to perform time-resolved experiments on proteins in aqueous solution. For my research I am focused on resolving the protonation dynamics within Cytochrome c Oxidase during its catalytic cycle.
Pit Langner born 1990 in Berlin, Germany
Bachelor of Science 2012, Freie Universiät Berlin
Master of Science 2015, Freie Universität Berlin
Previously I investigated proteins carrying a light-oxygen-voltage (LOV) domain for blue-light sensing via steady-state Fourier transform infrared (FTIR) and UV/Vis spectroscopy in conjunction with site-directed mutagenesis, H/D and H216O/H218O exchange and Stark labeling. Although obviously still in the field of biophysics, my research interest shifted when I started my PhD. Now I am utilizing the capabilities of the tunable QCL setup in combination with microfluidics and a flow-flash approach to primarily study (in close cooperation with Federico Baserga) the terminal enzyme of the respiratory chain, Cytochrome c Oxidase (CcO).
Kerruth, S., Langner, P., Raffelberg, S., Gärtner, W. and Heberle, J. (2017), Characterization of the Blue–Light-Activated Adenylyl Cyclase mPAC by Flash Photolysis and FTIR Spectroscopy. Photochem Photobiol, 93: 857–864. doi:10.1111/php.12746