Tue, 14:00 - 16:00 (0.1.01 Hörsaal B)
|Examination:||Written report (ca. 30 pages).|
|Inhalt:||The lecture introduces modern theoretical methods to study biological nano-machines. The focus is on nano-transporters. We introduce basic aspects of the structure and functioning of biological nano-transporters, and of bio-membranes. The following theoretical methods are addressed during the lecture: classical vs. combined quantum mechanical/molecular mechanical methods; transport of ions across bio-membranes; computations of free energy for nano-transporters. The lecture is accompanied by a tutorial consisting largely of practical computer work.|
|Literatur:||H. Kuhn and H.D. Försterling, Principles of Physical Chemistry. John Wiley & Sons 2000
V.A. Parsegian, Van der Waals Forces. A Handboock for biologists, chemists, engineers, and physicists. Cambridge 2006
K.E. van Holde, W.C. Curtis, and P.S. Ho, Principles of Physical Biochemistry. Prentice Hall 1998
D.J. Wales, Energy Landscapes - With applications to clusters, biomolecules, and glasses. Cambridge 2003
Additional literature will be indicated during the lecture.
Printouts of the lecture notes will be provided during the lecture.