AG Schlesinger

Genetic Biophysics

Dr. Ramona Schlesinger

Dr. Ramona Schlesinger
Dr. Ramona Schlesinger
AddressArnimallee 14
Building Fachbereich Physik — Room -1.1.15 and -1.1.12
D-14195 Berlin - Dahlem; Germany
Wheelchair AccessHandicapped ParkingElevator at least 140 x 110 cmHandicapped Bathroom
OfficeSieglinde Endrias
Telephone+49-30-838 53337
Fax+49-30-838 56510
EmailDr. Ramona Schlesinger
S. Endrias (Sekretariat)



Our research group is focusing on the elucidation of functioning of membrane proteins and subsequent signal transduction chains. To investigate proteins with biophysical methods the protein has to be available in quantitative amounts. We are using homologous and heterologous expression systems to produce the target proteins in sufficient amounts. To modify protein sequences we use molecular biological methods which lead to site-specific mutagenesis on DNA level. Such mutagenized protein molecules are investigated by spectroscopic methods as FTIR, Raman and EPR spectroscopy as well as used for crystallization to analyze by x-ray diffraction.