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Publikationen
2012
Nack, M., Radu, I., Schultz, B.-J.,Resler, T., Schlesinger, R., Bondar, A.-N., del Val, C., Abbruzzetti, S., Viappiani, C., Bamann, C., Bamberg, E., and Heberle
Kinetics of Proton Release and Uptake by Channelrhodopsin-2
FEBS Lett. 586, 1344-8 (2012)
2011
Kirchberg K, Kim TY, Möller M, Skegro D, Dasara Raju G, Granzin J, Büldt G, Schlesinger R, Alexiev U
Conformational dynamics of helix 8 in the GPCR rhodopsin controls arrestin activation in the desensitization process
Proc. Natl. Acad Sci USA 108, 18690-5 (2011)
Ballout F, Krassen H, Kopf I, Ataka K, Bründermann E, Heberle J, Havenith M
Scanning near-field IR microscopy of proteins in lipid bilayers
Phys. Chem. Chem. Phys. 13, 21432-21436 (2011)
Schleeger M, Radu, I., Heberle J.
‘Time-resolved FT-IR Spectroscopy for the Elucidation of Protein Function’,
in: "Supramoleclar Structure and Function 10",
Eds. Brnjas-Kraljevic, J., Pifat-Mrzljak, G., Springer, pp. 31-40 (2011)
Krassen H, Stripp ST, Böhm N, Berkessel A, Happe T, Ataka K, and Heberle J
Tailor-Made Modification of a Gold Surface for the Chemical Binding of a High-Activity [FeFe] Hydrogenase
Eur. J. Inorg. Chem. 2011, 1138–1146 (2011)
Shima S, Ataka K
Isocyanides inhibit [Fe]-hydrogenase with very high affinity
FEBS Lett. 585, 353-356 (2011)
Bauer C, Rabl C-R, Heberle J, Kottke T
Indication for a Radical Intermediate Preceding the Signaling State in the LOV Domain Photocycle
Photochem. Photobiol. 87, 548-553 (2011)
Radu I, Schleeger M, Nack M, Heberle J
Time-resolved FT-IR Spectroscopy of Membrane Proteins
Aust. J. Chem. 64, 9-15 (2011)
Krassen H, Ott S, and Heberle J
'In vitro' Hydrogen Production – using Energy from the Sun
Phys. Chem. Chem. Phys., 13, 47-57 (2011)
2010
Thamarath SS, Heberle J, Hore PJ, Kottke T, Matysik J.
Solid-State Photo-CIDNP Effect Observed in Phototropin LOV1-C57S by (13)C Magic-Angle Spinning NMR Spectroscopy.
J. Am. Chem. Soc., 132, 15542-43 (2010)
Jiang, X., Engelhard, M., Ataka, K. & Heberle, J.
‘Molecular Impact of the Membrane Potential on the Regulatory Mechanism of Proton Transfer in Sensory Rhodopsin II ’
J. Am. Chem. Soc. 132, 10808-15 (2010)
Ataka, K., Kottke, T. & Heberle, J.
‘Thinner, Smaller, Faster: IR Techniques To Probe the Functionality of Biological and Biomimetic Systems ’
Angew. Chem. Int. Ed. 49, 5416 - 5424 (2010)
Ataka, K., Kottke, T.& Heberle, J.
‘Dünner, kleiner, schneller - wie die IR-Spektroskopie zur Aufklärung des Funktionsmechanismus biologischer und biomimetischer Systeme beiträgt ’
Angew. Chem. 122, 5544 - 5553 (2010)
Radu I, Budyak IL, Hoomann T, Kim YJ, Engelhard M, Labahn J, Büldt G, Heberle J; Schlesinger R.
‘Signal relay from sensory rhodopsin I to the cognate transducer HtrI: Assessing the critical change in hydrogen-bonding between Tyr-210 and Asn-53 ’
Biophysical Chemistry 150, 23–28 (2010)
Nack M, Radu I, Gossing M, Bamann C, Bamberg E, von Mollard GF, Heberle J.
‘The DC gate in Channelrhodopsin-2: crucial hydrogen bonding interaction between C128 and D156 ’
Photochem Photobiol Sci. 9, 194-198 (2010)
2009
Krassen H, Schwarze A, Friedrich B, Ataka K, Lenz O, Heberle J.
‘Photosynthetic Hydrogen Production by a Hybrid Complex of Photosystem I and [NiFe]-Hydrogenase ’
ACS Nano. 3, 4055-4061(2009)
Radu I, Schleeger M, Bolwien C, Heberle J.
‘Time-resolved methods in biophysics. 10. Time-resolved FT-IR difference spectroscopy and the application to membrane proteins ’
Photochem Photobiol Sci. 8, 1517-1528 (2009)
Nack, M; Radu; I.; Bamann, C.; Bamberg, E.;Heberle, J.
‘The retinal structure of channelrhodopsin-2 assessed by resonance Raman spectroscopy’
FEBS Letters 583, 3676–3680 (2009)
Bahlawane, N., Ngamou, P.H., Vannier, V., Kottke, T., Heberle, J.& Kohse-Höinghaus, K.
‘Tailoring the properties and the reactivity of the spinel cobalt oxide ’
PhysChemChemPhys 11, 9224-9232 (2009)
Schleeger, M., Wagner, C., Vellekoop, M., Lendl, B., & Heberle, J.
‘Time-Resolved Flow-Flash FT-IR Difference Spectroscopy: The Kinetics of CO-Photodissociation from Myoglobin Revisited ’
Anal.Bioanal.Chem.394, 1869-1877 (2009)
An erratum to this article can be found at http://dx.doi.org/10.1007/s00216-009-2928-0
Radu, I., Bamann, C., Nack, M., Nagel, G., Bamberg, E., & Heberle, J.
‘Conformational Changes of Channelrhodopsin-2 ’
J. Am. Chem. Soc. 131, 7313-7319 (2009)
Krassen, H., Stripp, S., von Abendroth, G., Ataka, K., Happe, T., & Heberle, J.
‘Immobilization of the [FeFe]-Hydrogenase CrHydA1 on a Gold Electrode: Design of a Catalytic Surface for the Production of Molecular Hydrogen ’
J. Biotec. 142, 3-9 (2009)
Hiromoto T, Ataka K, Pilak O, Vogt S, Stagni MS, Meyer-Klaucke W, Warkentin E, Thauer RK, Shima S, Ermler U.
‘The crystal structure of C176A mutated [Fe]-hydrogenase suggests an acyl-iron ligation in the active site iron complex. ’,
FEBS Lett. 583, 585-590 (2009)
Pfeifer, A., Majerus, T., Zikihara, K., Matsuoka, D., Tokutomi, S., Heberle, J., & Kottke, T.
‘Time-Resolved Fourier Transform Infrared Study on Photoadduct Formation and Secondary Structural Changes within the Phototropin LOV Domain ’
Biophys. J. 96 , 1462-1470 (2009)
2008
Jiang, X., Zaitseva, E., Schmidt, M., Siebert,F., Engelhard, M., Schlesinger, R., Ataka, K., Vogel, R., & Heberle, J.
‘Resolving voltage-dependent structural changes of a membrane photoreceptor by surface-enhanced IR difference spectroscopy ’
Proc. Natl. Acad. Sci. USA 105, 12113-12117 (2008)
Ataka, K., Heberle, J.,
‘Bioenergetics at the gold surface: SEIRAS probes photosynthetic and respiratory reactions at the monolayer level ’
Biochem. Soc. Trans. 36, 986-991 (2008)
Jiang, X., Zuber, A., Heberle, J., Ataka, K.
‘ In situ monitoring of the orientated assembly of strep-tagged membrane proteins on the gold surface by surface-enhanced infrared absorption spectroscopy ’,
PhysChemChemPhys 10, 6381-6387 (2008)
Jiang, X., Ataka, K. & Heberle, J.,
‘ Influence of the Molecular Structure of Carboxyl Terminated Self-Assembled Monolayer on the Electron Transfer of Cytochrome C Adsorbed on an Au Electrode: in-Situ Observation by Surface Enhanced Infrared Absorption Spectroscopy ’,
J. Phys. Chem. C. 112, 813-819 (2008)
2007
Mironova, O. S., Budyak, I. L., Büldt, G., Schlesinger, R., & Heberle, J.,‘ FT-IR Difference Spectroscopy Elucidates Crucial Interactions of Sensory Rhodopsin I with the Cognate Transducer HtrI. ’,
Biochemistry 46, 9399-9405 (2007)
Majerus, T., Kottke, T., Laan, W., Hellingwerf, K., & Heberle, J.,
‘ Time-Resolved FT-IR Spectroscopy Traces Signal Relay within the Blue-Light Receptor AppA. ’,
ChemPhysChem. 8, 1787-1789 (2007)
Immeln, D., Schlesinger, R., Heberle, J., & Kottke, T.,
‘ Blue Light Induces Radical Formation and Autophosphorylation in the Light-sensitive Domain of Chlamydomonas Cryptochrome. ’,
J. Biol. Chem. 282, 21720–21728 (2007)
Gmelin, W., Zeth, K., Efremov, R., Heberle, J., Tittor, J., & Oesterhelt, D.,
‘ The Crystal Structure of the L1 Intermediate of Halorhodopsin at 1.9 Å Resolution. ’,
Photochem. Photobiol. 83, 369–377 (2007)
Haber-Pohlmeier, S., Abarca-Heidemann, K., Körschen, H.G., Kaur Dhiman, H., Heberle, J., Schwalbe, H., Klein-Seetharaman, J., Kaupp, U.B., & Pohlmeier, A.
‘ Binding of Ca2+ to glutamic acid-rich polypeptides from the rod outer segment. ’,
Biophys. J. 92, 3207–3214 (2007)
Ataka, K., & Heberle, J.,
‘ Biochemical applications of surface-enhanced infrared absorption spectroscopy. ’,
Anal. Bioanal. Chem. 388, 47–54 (2007)
Poetsch, A., Berzborn, R.J., Heberle, J., Link, T.A., Dencher, N.A., & Seelert, H.,
‘ Biophysics and Bioinformatics Reveal Structural Differences of the Two Peripheral Stalk Subunits in Chloroplast ATP Synthase. ’,
J. Biochem. 141, 411–420 (2007)
2006
Badura, A., Esper, B., Ataka, K., Grunwald, C., Wöll, C.,Kuhlmann, J., Heberle, J.& Rögner, M.,‘ Light-Driven Water Splitting for (Bio-)Hydrogen Production: Photosystem 2 as the Central Part of a Bioelectrochemical Device ’,
Photochem. Photobiol. 82, 1385–1390
Mulkidjanian, A.Y., Heberle, J., & Cherepanov, D.A.,
‘Protons @ interfaces: Implications for biological energy conversion’,
Biochim. Biophys. Acta 1757, 913-930
Hrabakova, J., Ataka, K., Heberle , J., Hildebrandt, P., & Murgida, D.,
‘Long distance electron transfer in cytochrome c oxidase immobilised on electrodes. A surface enhanced resonance Raman spectroscopic study’,
Phys. Chem. Chem. Phys. 8, 759 - 766
Pereira, M.M., Sousa, F.L., Teixeira, M., Nyquist, R.M., & Heberle, J.,
‘A tyrosine residue deprotonates during oxygen reduction by the caa3 reductase from Rhodothermus marinus’,
FEBS Letters 580, 1350–1354
Kottke, T., Ahmad, M., Batschauer, A., & Heberle, J.,
‘Blue-Light-Induced Changes in Arabidopsis Cryptochrome 1 Probed by FTIR Difference Spectroscopy’,
Biochemistry 45, 2472-2479
Ataka, K., Richter, B., & Heberle, J.,
‘Orientational control on the physiological reaction of cytochrome c oxidase tethered to a gold electrode’,
J. Phys. Chem. B. 110, 9339-9347.
Kottke, T., Dick, B., Hegemann, P., & Heberle, J.,
‘The Photochemistry of the LOV Domains in the Algal Blue Light Receptor Phot’,
Biopolymers 82, 373-378.
Ataka, K., & Heberle, J.,
‘Use of Surface Enhanced Infrared Absorption Spectroscopy (SEIRA) to probe the functionality of a protein monolayer’,
Biopolymers 82, 415-419.
Gensch, T., Heberle, J., Viappiani, C. (2006) eds.,
Special Issue on: ‘Proton transfer in biological systems’,
Photochem Photobiol Sci 5, 529-530.
Efremov, R., Gordelyi, V. I., Heberle, J., & Büldt, G.,
‘Time-resolved microspectroscopy on a single crystal of bacteriorhodopsin reveals lattice induced differences in the photocycle kinetics’,
Biophys. J. 91, 1441–1451
2005
Mulkidjanian, A.Y., Cherepanov, D.A., Heberle, J., & Junge, W.,‘Proton transfer dynamics at membrane/water interface and mechanism of biological energy conversion’,
Biochemistry (Mosc). 70, 251-256
Heberle, J.,
´Vibrational spectroscopy explores the photoreaction of LOV domains´ in: Light Sensing in Plants (edited by Wada, M., Simazaki, K., & Iino, M.), Springer, Berlin, pp. 155-161
Mironova, O. S., Efremov, R. G., Person, B., Heberle, J.,Budyak, I. L., Büldt, G., & R. Schlesinger,
‘Functional characterization of sensory rhodopsin II from Halobacterium salinarum expressed in Escherichia coli’,
FEBS Lett. 579, 3147-3151
Habuchi, S., Cotlet, M., Gensch, T., Bednarz, T., Haber-Pohlmeier, S., Rozenski, J., Dirix, G., Michiels, J., Vanderleyden, J., Heberle, J., De Schryver, F.C., & Hofkens, J.
‘Cis-trans Isomerization and Decarboxylation in the Photoconversion of the Red Fluorescent Protein DsRed’,
J. Am. Chem. Soc. 127, 8977-8984
Mayer, D., Ataka, K., Heberle, J. & Offenhäusser, A.,
‘Scanning Probe Microscopic Studies of the Oriented Attachment and Membrane Reconstitution of Cytochrome c oxidase to a Gold Electrode’,
Langmuir 21, 8580-8583
Heberle, J.,
‘The dynamics of proton transfer across bacteriorhodopsin explored by FT-IR spectroscopy´ in: Biophysical and Structural Aspects of Bioenergetics (edited by Wikström, M), Royal Society of Chemistry, CambridgeUK, pp. 249-267
2004
Heberle, J., & Ataka, K.,´SEIDAS: Oberflächenverstärkte IR-Differenzspektroskopie zur funktionellen Untersuchung von Proteinmonolagen,
BIOspektrum 10, 42-44
Nyquist, R.M., Ataka, K., & Heberle, J.,
´The Molecular Mechansism of Membrane Proteins Probed by Evanescent Infrared Waves´,
ChemBioChem 3, 431-436
Bednarz, T., Losi, A., Gärtner, W., Hegemann, P. & Heberle, J.,
‘Functional variations among LOV domains as revealed by FTIR difference spectroscopy’,
Photochem. Photobiol. Sci. 3, 575-579
Ataka, K., & Heberle, J.,
‘Functional vibrational spectroscopy of a cytochrome c monolayer: SEIDAS probes the interaction with different surface modified electrodes’,
J. Am. Chem. Soc. 126, 9445-9457
Heberle, J.,
‘A local area network of protonated water molecules’,
Biophys. J. 87, 2105-2106
Gieß, F., Friedrich, M., Heberle, J., Naumann, R., Knoll, W.,
‘The Protein Tethered Lipid Bilayer – a novel mimic of the biological membrane’,
Biophys. J. 87, 3213-3220
Friedrich, M., Gieß, F., Naumann, R., Knoll, W., Ataka, K., Heberle, J., Hrabakova, J., Murgida, D., & Hildebrandt, P.,
‘Active site structure and redox processes of cytochrome c oxidase immobilised in a novel biomimetic lipid membrane on an electrode’,
Chem. Comm. 21, 2376 –2377
Laan, W., Bednarz, T., Heberle, J., & Hellingwerf, K.,
‘Chromophore composition of a heterologously expressed BLUF-domain’,
Photochem. Photobiol. Sci. 3, 1011-1016
Ataka, K., Giess, F., Knoll, W., Naumann, R., Haber-Pohlmeier, S., Richter, B., & Heberle, J.,
‘Oriented attachment and membrane reconstitution of His-tagged cytochrome c oxidase to a gold electrode: in-situ monitoring by Surface Enhanced Infrared Absorption Spectroscopy’,
J. Am. Chem. Soc. 126, 16199-16206
2003
Ataka, K., Hegemann, P., & Heberle, J.,´Vibrational Spectroscopy of an Algal Phot-LOV1 Domain Probes the Molecular Changes Associated with Blue-light Reception´,
Biophys. J. 84, 466-474
Kottke, T., Heberle, J., Hehn, D., Dick, B., & Hegemann, P.,
´Phot LOV1: Photocycle of a Blue Light Receptor Domain from the Green Alga Chlamydomonas reinhardtii´,
Biophys. J. 84, 1192-1201
Gordeliy, V.I., Schlesinger, R., Efremov, R., Büldt, G., Heberle, J.,
´Crystallization in lipidic cubic phases: A case study with Bacteriorhodopsin ´
In: Methods in Molecular Biology Vol. 228: Membrane Protein Protocols: Expression, Purification, and Crystallization (edited by B. Selinsky), Humana Press,
Totowa,NJ, pp. 305-316
Haker, A., Hendriks, J., van Stokkum, I.H.M., Heberle, J., Hellingwerf, K.J.,Crielaard, W., & Gensch, T.,
´The Two Photocycles of Photoactive Yellow Protein from Rhodobacter sphaeroides´,
J. Biol. Chem. 278, 8442-8451
Ataka, K., & Heberle, J.,
´Electrochemically induced Surface Enhanced Infrared Difference Absorption (SEIDA) spectroscopy of a protein monolayer´,
J. Am. Chem. Soc. 125, 4986-4987
Nyquist, R.M., Heitbrink, D., Bolwien, C., Gennis, R.B. & Heberle, J.,
´Direct Observation of Protonation Reactions during the Catalytic Cycle of Cytochrome c Oxidase´,
Proc. Natl. Acad. Sci. USA 100, 8715-8720
Lepke, S., Heberle, J., & Passow, H.,
´The Band 3 Protein: Anion Exchanger and Anion-Proton Cotransporter’ in: Red Cell Membrane Transport in Health and Disease (edited by Bernhardt, I. & Ellory, J.C.), Springer, Berlin, pp. 221-252
Poetsch, A., Rexroth, S., Heberle, J., Link, T.A., Dencher, N.A., & Seelert, H.,
´Characterisation of subunit III and its oligomer from spinach chloroplast ATP synthase´,
Biochim. Biophys. Acta 1618, 59-66
2002
Heitbrink, D., Bolwien, C., Sigurdsson, H., Brzesinski, P. & Heberle, J.,´Transient binding of CO to CuB in cytochrome c oxidase is dynamically linked to structural changes around a carboxyl group: a time-resolved step-scan Fourier transform infrared investigation´,
Biophys. J. 82, 1-10
Büldt, G., & Heberle, J.,
´Biological Nanomachines´, in: Soft matter: Complex materials on mesocopic scale, Schriften des Forschungszentrums Jülich, Vol. 10, B15
Tittor, J., Paula, S., Subramaniam, S., Heberle, J., Henderson, R. & Oesterhelt, D.,
´Proton translocation by Bacteriorhodopsin in the Absence of Substantial Conformational Changes´,
J. Mol. Biol. 319, 555-565
Friedrich, T., Geibel, S., Ataka, K., Kalmbach, R., Chizov, I., Heberle, J., Engelhard, M., & Bamberg, E.,
´Proteorhodopsin is a Light-driven Proton Pump with Variable Vectoriality´,
J. Mol. Biol. 321, 821-838
2001
Heberle,J., & Gensch, T.,´When FT-IR spectroscopy meets X-ray crystallography´,
Nature Struct. Biol. 8, 195-197
Zscherp, C., Schlesinger, R., & Heberle, J.,
´Time-resolved FT-IR Spectroscopic Investigation of the pH-dependent Proton Transfer Reactions in the E194Q Mutant of Bacteriorhodopsin´,
Biochem. Biophys. Res. Comm. 283, 57-63
Nyquist, R.M., Heitbrink, D., Bolwien, C., Wells, T.A., Gennis, R.B. & Heberle, J.,
´Perfusion-induced redox differences in cytochrome c oxidase: ATR-FTIR spectroscopy´,
FEBS Lett. 505, 63-67
2000-1990
von Bergen, M., Friedhoff, P., Biernat, J., Heberle, J., Mandelkow, E.-M., Mandelkow, E.´Assembly of t protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming beta structure`,
Proc. Natl. Acad. Sci. USA 97, 5129-5134
Heberle, J. *,
´Proton Transfer Reactions Across Bacteriorhodopsin and Along the Membrane`,
Biochim. Biophys. Acta 1458, 135-147
Heberle, J., Fitter, J., Sass, H.J. & Büldt, G. *,
´Bacteriorhodopsin: The functional details of a molecular machine are being resolved´,
Biophys. Chem. 85, 229-248
Fitter, J. & Heberle, J.,
´Structural equilibrium fluctuations and thermal stability of mesophilic and thermophilic a-amylase´,
Biophys. J. 79, 1629-1636
Zscherp, C., Schlesinger, R., Tittor, J., Oesterhelt, D., & Heberle, J.,
´In-situ Determination of Transient pKa Changes of Internal Amino Acids of Bacteriorhodopsin using Time-Resolved Attenuated Total Reflection Fourier-Transform Infrared Spectroscopy ´,
Proc. Natl. Acad. Sci. USA 96, 5498-5503
Büldt, G., Heberle, J., Schlesinger, R. & Sass, H.J. *,
´Structure, dynamics, and function of the proton pump bacteriorhodopsin´,
in: Methods in Protein Structure Analysis (Ed. Roza, Maria Kamp), Springer Verlag, Berlin, pp. 225-239
Heberle, J. *,
`Time-resolved ATR/FT-IR spectroscopy of Membrane Proteins`,
Recent Research Developments in Applied Spectroscopy (S. G. Pandalai, ed.), Research Signpost, Trivandrum, pp. 147-159
Heberle, J., Büldt, G., Koglin, E., Rosenbusch, J. P., & Landau, E. M.,
´Assessing the Functionality of a Membrane Protein in a Three-Dimensional Crystal´,
J. Mol. Biol. 281, 587-592
Büldt, G., Heberle, J., Dencher, N.A. & Sass, H.J.,
´Structure, dynamics, and function of bacteriorhodopsin´,
J. Protein Chem. 17, 536-538
Zscherp, C., & Heberle, J.,
´Infrared difference spectra of the intermediates L, M, N, and O of the Bacteriorhodopsin photoreaction obtained by time-resolved attenuated total reflection spectroscopy´,
J. Phys. Chem. 101, 10542-10547
Heberle, J., & Zscherp, C.,
´pH-dependence of proton transfer reactions within Bacteriorhodopsin: A time-resolved ATR/FT-IR study´,
in: Spectroscopy of Biological Molecules, Modern Techniques (Ed. P. Carmona, et al.), Kluwer Academic Publishers, Dordrecht, Niederlande, pp. 117-118
Riesle, J., Oesterhelt, D., Dencher, N.A. & Heberle, J.,
´D38 is an essential part of the proton translocation pathway in Bacteriorhodopsin´,
Biochemistry 35, 6635-6643
Heberle, J., & Zscherp, C.,
´ATR/FT-IR difference spectroscopy of biological matter with microsecond time resolution´,
Appl. Spectrosc. 50, 588-596
Zscherp, C., Büldt, G., & Heberle, J.,
´Time-resolved ATR/FT-IR measurements of the Bacteriorhodopsin photocycle´, in: Spectroscopy of Biological Molecules (Ed. J.C. Merlin, et al.), Kluwer Academic Publishers, Dordrecht, Niederlande, pp. 177-178
Hoffmann, A., Hildebrandt, V., Heberle, J. & Büldt, G.,
´Photoactive mitochondria: In vivo transfer of a light-driven proton pump into the inner mitochondrial membrane of Schizosaccharomyces pombe´,
Proc. Natl. Acad. Sci. USA 91, 9367-9371
Heberle, J., Riesle, J., Thiedemann, G., Oesterhelt, D. & Dencher, N.A.,
´Proton migration along the membrane surface and retarded surface to bulk transfer´,
Nature 370, 379-382
Heberle, J., Oesterhelt, D. & Dencher, N.A.,
´Decoupling of photo- and proton cycle in the Asp85Glu mutant of Bacteriorhodopsin´,
EMBO J. 12, 3721-3727
Hildebrandt, V., Fendler, K., Heberle, J., Hoffmann, A., Bamberg, E. & Büldt, G.,
´Bacteriorhodopsin expressed in Schizosaccharomyces pombe pumps protons through the plasma membrane´,
Proc. Natl. Acad. Sci. USA 90, 3578-3582
Heberle, J. & Dencher, N.A.,
´Surface-bound optical probes monitor proton translocation and surface potential changes during the Bacteriorhodopsin photocycle´,
Proc. Natl. Acad. Sci. USA 89, 5996-6000
Heberle, J. & Dencher, N.A.,
´Proton transfer in the light-harvesting membrane protein bacteriorhodopsin - An investigation with optical pH-indicators´,
in: Proton Transfer in Hydrogen-Bonded Systems (Ed. T. Bountis), NATO ASI Series B Physics, Vol. 291, Plenum Press, New York, pp. 187-197
Heberle J. & Dencher, N.A.,
´The surface of the purple membrane: A transient pool for protons ?´,
in: Structures and Functions of Retinal Proteins (Ed. J.L. Rigaud), Colloque INSERM/John Libbey Eurotext Ltd., Vol. 221, pp. 221-224
Dencher, N.A., Büldt, G., Heberle, J., Höltje, H.-D. & Höltje, M.,
´Light-triggered opening and closing of an hydrophobic gate controls vectorial proton transfer across Bacteriorhodopsin´,
in: Proton Transfer in Hydrogen-Bonded Systems (Ed. T. Bountis), NATO ASI Series B Physics, Vol. 291, Plenum Press, New York, pp. 171-185
Dencher, N.A., Heberle, J., Büldt, G., Höltje, H.-D. & Höltje, M.,
´What do neutrons, X-ray synchrotron radiation, optical pH-indicators, and mutagenesis tell us about the light-driven proton pump Bacteriorhodopsin ?´,
in: Membrane Proteins: Structures, Interactions and Models (Eds. Pullmann et al.), Kluwer Academic Publishers, Dordrecht, Niederlande, pp. 69-84
Dencher, N.A., Heberle, J., Büldt, G., Höltje, H.-D. & Höltje, M.,
´Active and passive proton transfer steps through Bacteriorhodopsin are controlled by a light-triggered hydrophobic gate´,
in: Structures and Functions of Retinal Proteins (Ed. J.L. Rigaud), Colloque INSERM/John Libbey Eurotext Ltd., Vol. 221, pp. 213-216
Thiedemann, G., Heberle, J. & Dencher, N.A.,
´Bacteriorhodopsin pump activity at reduced humidity´,
in: Structures and Functions of Retinal Proteins (Ed. J.L. Rigaud), Colloque INSERM/John Libbey Eurotext Ltd., Vol. 221, pp. 217-220
Dencher, N.A., Heberle, J., Bark, C., Koch, M.H.J., Rapp, G., Oesterhelt, D., Bartels, K. & Büldt, G.,
´Proton translocation and conformational changes during the Bacteriorhodopsin photocycle: Time-resolved studies with membrane-bound optical probes and X-ray diffraction´,
Photochem. Photobiol. 54, 881-887
Heberle, J. & Dencher, N.A. (1990),
´Bacteriorhodopsin in ice - Accelerated proton transfer from the purple membrane surface´,
FEBS Lett. 277, 277-280
[*] Reviews
