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Theory on linear viscoelasticity of a cytoskeletal network

Jun 16, 2016 | 04:00 PM

Prof. Dr. Tetsuya Hiraiwa, Department of Physics, Faculty of Science The University of Tokyo, JAPAN

Mechanical properties of a cortical cytoskeleton govern the elastic and viscous resistanc- es of living cells to deformation and are crucial for wide variety of cellular functions. A cortical cytoskeleton is the network consisting of actin filaments and crosslinker proteins located underneath the cell membrane. In this talk, I would like to present a theoretical method to calculate linear viscoelasticity of such filamentous network from given properties of single segments. Using the presented method, we find that the robust power-law behavior in complex moduli with respect to the frequency of external forcing on the intermediate frequency window, which is observed in several experiments and numerical simulation, is attributed to the self-similarity of tension propagation and that the observed power law exponent, 1/2, is due to the angular chain decorrelations at network nodes.

Time & Location

Jun 16, 2016 | 04:00 PM

Seminar Room T2 (1.4.03)