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Advanced Biophysics 2022

20114101 VORLESUNG

Lecturer: Joachim Heberle, Jacek Kozuch, Sabine Oldemeyer
Language: English
Period: 19.04.2022 - 22.07.2022
Dates: Tue 12:00-14:00, Fri 12:00-14:00 - Lecture Hall A

max. number of participants

unlimited
Notes: 10 ECTS only together with practical course 20114130.
Content: This module will present and substantiate biophysical methods and concepts. Selected methods like spectroscopy and diffraction and their application to proteins, nucleic acids and biomembranes are of particular relevance. The lecture series will cover a selection of the following methods: absorption spectroscopy in the UV, visible and IR region; fluorescence spectroscopy, time-resolved approaches; spectroscopy with linear and circular polarized light; vibrational spectroscopy: Fourier-transform infrared (FTIR), resonance Raman, surfance-enhanced Raman and IR; diffraction with X-rays, Neutrons and electrons; crystallization and protein crystallography; nuclear magnetic resonance (NMR); light scattering; single molecule spectroscopy; optical tweezer; atomic force microscopy; theoretical methods: MD simulations, Poisson-Boltzmann, QM/MM
Literature: Since a comprehensive textbook in Biophysics is not available, here is a list of books from which parts will be used in the lecture: Serdyuk, I.N., Zaccai, N.R. & Zaccai, J: Methods in Molecular Biophysics. Tuszynski & Kurzynski: Introduction to Molecular Biophysics. Cantor & Schimmel: Biophysical Chemistry. Walla: Modern Biophysical Chemistry. Brandén & Tooze: Introduction to Protein Structure. Winter & Noll: Methoden der Biophysikalischen Chemie. Gennis: Biomembranes
Contact: joachim.heberle@fu-berlin.de, jacek.kozuch@fu-berlin.de, sabine.oldemeyer@fu-berlin.de

Lecture Slides

Vorl01_19042022

Vorl02_22042022

Vorl03_26042022

Vorl04_29042022

Vorl05_03052022

Vorl05b_06052022

Vorl06a_10052022

Vorl06b_13052022

Vorl07a_17052022

Vorl07b_20052022

Vorl08a_24052022

Vorl08a_01062022_Neutrons

Vorl08b_03062022_NMR

Vorl09a_07062022_QM

Vorl09b_10062022_MM

Vorl10a_14062022_VibSpecIntro

Vorl10b_17062022_IRSpec

Vorl11a_21062022_Raman

Vorl11b_24062022_SERS_SEIRAS

Vorl12a_28062022

Vorl12b_01072022

Vorl13a_05072022

Vorl13b_08072022

Vorl15a_12072022

Vorl15b_15072022

Vorl16a_19072022

For physicists affected by the war in Ukraine