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CRC 498 - Protein-Cofactor Interactions in Biological Processes (2000-2009)

SFB 498

SFB 498

Nature utilizes protein-cofactor interactions in order to optimize biological functions. The research center focused on the investigation of the interaction of the protein with organic cofactors and metal ions. These interactions were investigated using an approach combining various techniques from molecular biology, biochemistry, structure analysis, spectroscopy and theory.

The collaborative research centre consisted of seventeen scientific projects grouped according to the research goals focussed on the biological processes of electron and excitation energy transfer, conformational changes and signal transduction, and enzymatic cleavage of molecular hydrogen and water oxidation.


Prof. Dr. Robert Bittl

Involved groups

Research Group Antontik / Stehlik, Research Group Weber, Research Group Haumann / Dau, Research Group Heyne

Participating institutions

  • Freie Universität
  • Charité - Universitätsmedizin Berlin
  • Humboldt University Berlin
  • Technical University Berlin
  • Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)