CRC 1078: Protonation Dynamics in Protein Function (2013 - 2024)
How do proteins function? Which mechanisms are effective in the regulation of processes by proteins?
The central research goal was to identify and understand a new key principle in protein science – the control and coordination of complex protein function by protonation dynamics. The findings from this fundamental biophysical research could be used to develop novel concepts for regenerative energy production, such as splitting water into hydrogen and oxygen by sunlight.
Spokesperson
Professor Dr. Holger Dau (2013 - 2017)
Professor Dr. Joachim Heberle (2017 - 2024)
Involved research groups
Alexiev, Clementi, Dau, Heberle, Heyne, Kozuch, Netz, Schlesinger as well as Block, Imhof, Bondar
Key figures
- € 29.3 m of public funding
- more than 400 publications
- 9 professorial appointments
- 32 doctorates completed
Participating institutions
- Freie Universität Berlin
- Technische Universität Berlin
- Humboldt-Universität zu Berlin
- Charité - Universitätsmedizin Berlin
- Leibniz-Institut für Molekulare Pharmakologie
- Justus-Liebig-Universität Gießen
- Hebrew University of Jerusalem in Israel